Shop Advantage II

There is an abundance of flea products out on the market. Some prevent various other types of insects while others target specific insects. Depending on your pets needs, your selection in insect repellent will vary. If you’ve noticed your pet being affected by fleas or lice, there is a product designed specifically to help you.

Table of Contents

  1. What is Advantage II?
  2. Benefits:
  3. How it works:
  4. Shop Advantage II

Advantage II is a product that is great for homes with multiple pets as other products will require you to keep cats and dogs separated upon use for 24 hours. Advantage II is useable for cats and dogs, meaning separation is not necessary. Continue reading to learn more about Advantage II.

What is Advantage II?

Advantage II is a monthly flea preventative for dogs and cats that offers comprehensive flea protection by killing adult fleas, larvae, and eggs. Advantage II also treats, prevents, and controls lice on dogs. Advantage II does not kill ticks, so we recommend using the Preventic Tick Collar along with Advantage II (dogs only).

Advantage II is for Dogs 7 weeks of age or older and Cats 8 weeks of age or older.


  • Kills fleas within 12 hours of application
  • Kills all flea life stages including flea eggs and larvae to prevent infestation
  • Treats, prevents, and controls lice infestations (dogs only)
  • Safe and easy to apply
  • Waterproof – remains effective even if pet gets wet

How it works:

The first active ingredient is imidacloprid, which acts on the nervous system of the flea to cause paralysis and subsequent death. Within 12 hours of application, 98-100 percent of fleas are dead. The second active ingredient, pyriproxyfen, is an insect growth regulator. Once a female flea lays her eggs, pyriproxyfen works to prevent the eggs from hatching, ending the flea life cycle.

Shop Advantage II

Thanks to 1-800-PetMeds you have the ability to shop for Advantage II without leaving your home! The following are select Advantage products available online for purchase. To learn more about each individual product simply click the title or image below.